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KMID : 0356919960300030245
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Korean Journal of Anesthesiology
1996 Volume.30 No. 3 p.245 ~ p.251
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Comparative Effects of Halothane, Enflurane and Isoflurane on the Mouse Two-cell Embryo Development
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Abstract
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Background:
@EN Heart rate variability provides us with many informations of autonomic activities of cardiovascular system. Among the many methods of analyzing R-R variability, power spectral analysis is understood to be most useful, quantitative, and
noninvasive
method with repressents the changes of frequency. And the power spectral density is composed of three components in power, a high frequency at 0.15~0.5Hz, a middle frequency at 0.10~015Hz, and a low frequency at 0.04~0.08Hz.
@ES Methods:
@EN The each frequency power of the RR interval variability was checked in the 8 mongorean dogs according to the changes in end tidal concentration of halothane, enflurane and isoflurane, and the relationship was measured.
@ES Results:
@EN The power of three frequency bands decreased at 1.0 and 1.5MAC and increased at 2.0MAC halothane compared with previous MAC respectively. The power increased at 1.0 and 1.5MAC and decreased at 2.0MAC enflurane compared with previous MAC
respectively. There was no correlation between the power of three frequency bands and the changes of end tidal concentration of isoflurane. The low/high ratio associated with the changes of tidal concentration of inhalation anesthetics increased
at
1.0
and 1.5MAC and decreased at 2.0MAC compared with previous MAC respectively.
@ES Conclusion:
@EN In out study we confirmed that spectral analysis of R-R interval variability might reflect the balance between sympathetic and parasympthetic activity and low/high ratio would be a convenient index of such interaction during anesthesia within
the
clinical range of end tidal concentration of inhalation anesthetics. (Korean J Anesthesiol 1996; 30: 252~263)
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KEYWORD
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